![]() Finally, anyone over 40 years old should be treated with KI only if the predicted exposure is high enough to destroy the thyroid and induce lifelong hypothyroidism (thyroid deficiency).Ĥ. What potassium iodide (KI) products are currently available? Anyone over 18 years old and up to 40 years old should be treated at a slightly higher threshold. The recommendation is to treat them at the lowest threshold (with respect to predicted radioactive dose to the thyroid). Those at highest risk are infants and children, as well as pregnant and nursing females because of the potential for KI to suppress thyroid function in the developing fetus and the newborn. The FDA guidance prioritizes groups based on age, which is the primary factor for determining risk for radioiodine-induced thyroid cancer. Who really needs to take potassium iodide (KI) after a nuclear radiation release? It is not a general radioprotective agent.ģ. Potassium iodide (KI) works only to prevent the uptake of radioactive iodine into the thyroid gland. KI floods the thyroid with non-radioactive iodine and prevents the uptake of the radioactive molecules, which are subsequently excreted in the urine.Ģ. Can potassium iodide (KI) be used to protect against radiation from bombs other than radioactive iodine, such as radiation from a dirty bomb? When administered in the recommended dose, KI is effective in reducing the risk of thyroid cancer in individuals or populations at risk for inhalation or ingestion of radioiodines. The effectiveness of KI as a specific blocker of thyroid radioiodine uptake is well established. How do I know that potassium iodide (KI) will be available in case of an emergency? Should I buy potassium iodide (KI) to keep on hand? Should I check with my doctor before I take potassium iodide (KI)?Īs a doctor, should I recommend potassium iodide (KI) for my patients who request it? What are the side effects of potassium iodide (KI)? Who should not take potassium iodide (KI) or should have restricted use? When should I take potassium iodide (KI)?įor how long should I take potassium iodide (KI)? ![]() What dosages of potassium iodide (KI) should be taken for specific exposure levels? What potassium iodide (KI) products are currently available? ![]() This guidance updates FDA’s 1982 recommendations.Ĭan potassium iodide (KI) be used to protect against radiation from bombs other than radioactive iodine, such as radiation from a dirty bomb? The recommendations in the guidance address KI dosage and the projected radiation exposure at which the drug should be used. The adoption and implementation of the recommendations are at the discretion of the state and local governments responsible for developing regional emergency-response plans related to radiation emergencies. The objective of the document is to provide guidance to other Federal agencies, including the Environmental Protection Agency (EPA) and the Nuclear Regulatory Commission (NRC), and to state and local governments regarding the safe and effective use of potassium iodide (KI) as an adjunct to other public health protective measures in the event that radioactive iodine is released into the environment. In December 2001, the Food and Drug Administration (FDA) issued a final Guidance on Potassium Iodide as a Thyroid Blocking Agent in Radiation Emergencies) (PDF - 40 KB). ![]()
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